(Pictures and Display from the RCSB Protein Data Bank Website)



Title

Structure

PDB-code

Reference

Display

Caspase-3 in Complex with DARPin

 

 

2Y0B
2XZD
2XZT

 

Barandun, J. et al.,

(2011)

 

2Y0B
2XZD
2XZT

Caspase-8 in Complex with DARPin

 

 

2Y1L

 

Barandun, J. et al.,

(2011)

 

2Y1L

In Silico Identification and Crystal Structure Validation of Caspase-3 Inhibitors without a P1 Aspartic Acid Moiety.

 

 

2XYP
2XYH
2XYG

 

Ganesan, R., et al.,
Acta Crystallogr.,Sect.F v67 pp842-850
(2011)

 

2XYP
2XYH
2XYG

Designed ankyrin repeat protein binders for the crystallization of AcrB: Plasticity of the dominant interface

 

 

3NOC
3NOG

 

Monroe, N., et al.,
J.Struct.Biol.v174 pp269-281
(2010)

 

3NOC
3NOG

High-resolution structure of native Malus domestica ACC synthase

 

 

3PIU

 

Scharer, M.A., et al.,
Febs Lett. v585 pp111-114
(2010)

 

3PIU

Structural determinants for improved stability of designed ankyrin repeat proteins with a redesigned C-capping module.

 

 

2XEE
2XEH
2XEN

 

Kramer, M., et al.,
J.Mol.Biol.v404 pp381-391
(2010)

 

2XEE
2XEH
2XEN

Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism.

 

 

3MBB
3MC6
3MAD
3MAF
3MAU

 

Bourquin, F., et al.,
Structure v18 pp1054-1065
(2010)

 

3MBB
3MC6
3MAD
3MAF
3MAU

Crystal Structure of Human Pyrin B30.2 Domain

 

 

2WL1

 

Weinert C., et al.,
J.Mol.Biol. v394 pp.226-236
(2009)

 

2WL1

Crystal structure of GAD1 from Arabidopsis thaliana

 

 

3HBX

 

Gut H.,et al.,
J.Mol.Biol. v392 pp.2334-351
(2009)

 

3HBX

Crystal structure of Ost6L

 

 

3G7Y
3G9B
3GA4

 

Stirnimann C.U.,et al.,
Proc.Natl.Acad.Sci.USA v106 pp.11061-6
(2009)

 

3G7Y
3G9B
3GA4

Crystal Structure of the Multidrug Exporter Mexb from Pseudomonas Aeruginosa

 

 

2V50

 

Sennhauser G,et al.,
J.Mol.Biol. v389 pp.134-45
(2009)

 

2V50

Structure of the Catalytic Domain of Procaspase-8

 

 

2K7Z

 

Keller N.,et al.,
Structure v17 pp.438-448
(2009)

 

2K7Z

Structure of the Transforming Growth Factor-Beta Neutralizing Antibody GC-1008

 

 

3EO0

 

Wilkinson T.,et al.,
Proc.Natl.Acad.Sci.Usa v105 pp.20251-6
(2008)

 

3EO0

Structure of the Fab Fragment of GC-1008 in Complex with Transforming Growth Factor-Beta 3

 

 

3EO1

 

Wilkinson T.,et al.,
Proc.Natl.Acad.Sci.Usa v105 pp.20251-6
(2008)

 

3EO1

Structure of the Recombinant Antibody Fab Fragment F3P4

 

 

2V7N

 

Frey D.,et al.,
Acta Crystallogr.,Sect.D v64 pp.636
(2008)

 

2V7N

Crystal Structure of the Vps4p-dimer

 

 

2RKO

 

Hartmann C.,et al.,
J.Mol.Biol. v377 pp.352-63
(2008)

 

2RKO

Inhibition of caspase-2 by a designed ankyrin repeat protein (DARPin)

 

 

2P2C

 

Schweizer A.,et al.,
Structure v15 pp.625-36
(2007)

 

2P2C

Drug Export Pathway Of Multidrug Exporter ACRB Revealed By DARPin Inhibitors

 

 

2J8S

 

Sennhauser, G., et al.,
PLoS Biol. v5 e.7
(2007)

 

2J8S

Crystal Structure Of Caspase-3 In Complex With Aza-Peptide Epoxide Inhibitors

 

 

2CNN
2CDR

 

Ganesan R.,et al.,
Biochemistry v45 pp.9059
(2006)

 

2CNN
2CDR

Crystal Structure Of E3_19 An Designed Ankyrin Repeat Protein

 

 

2BKG

 

Binz, H.K., et al.,
Proteins: Struct., Funct., Bioinf. v65 pp.280-284
(2006)

 

2BKG

Crystal Structures Of Caspase-3 In Complex with AZA-Peptide Michael Acceptor Inhibitors

 

 

2C1E
2C2K
2C2M
2C2O
2C2Z

 

Ekici, O.D., et al.,
J.Med.Chem. v49 pp.5728-5749
(2006)

 

2C1E
2C2K
2C2M
2C2O
2C2Z

HDM2 In Complex With A Beta-Hairpin

 

 

2AXI

 

Fasan, R., et al.,
Chembiochem v7 pp.515-526
(2006)

 

2AXI

Crystal Structures Of Dimethylarginine Dimethylaminohydrolase
Crystal Form I, Form II,
In Complex with Citrulline,
In Complex with S-Nitroso-L-Homocysteine,
In Complex with L-Homocysteine,
Bound with Zinc at low pH,
Bound with Zinc at high pH

 

 

2CI3
2CI4
2C6Z
2CI1
2CI5
2CI6
2CI7

 

Frey, D., et al.,
Structure v14 pp.901-911
(2006)

 

2CI3
2CI4
2C6Z
2CI1
2CI5
2CI6
2CI7

Crystal Structures Of Caspase-3 In Complex With AZA-Peptide Epoxide Inhibitors

 

 

2CDR
2CNK
2CNL
2CNN
2CNO

 

Ganesan, R., et al.,
Biochemistry v45 pp.9059-9067
(2006)

 

2CDR
2CNK
2CNL
2CNN
2CNO

Extended Substrate Recognition In Caspase-3 Revealed By High Resolution X-Ray Structure Analysis

 

 

2CJX
2CJY
2DKO

 

Ganesan, R., et al.,
J.Mol.Biol. v359 pp.1378-1388
(2006)

 

2CJX
2CJY
2DKO

Crystal Structure Of The PRYSPRY Domain

 

 

2FBE

 

Grütter, C., et al.,
Febs Lett. v580 pp.99-106
(2006)

 

2FBE

Crystal Structures Of Escherichia coli GadB: In An Autoinhibited State (Aldamine,N-Terminal Deletion Mutant),
In Complex With Bromide,
In Complex With Iodide

 

 

2DGK
2DGL
2DGM

 

Gut, H., et al.,
Embo J. v25 pp.2643-2651
(2006)

 

2DGK
2DGL
2DGM

Crystal Structure Of The C-Terminal Domain Of The Electron Transfer Catalyst DsbD
Oxidized Form,
Reduced Form,
Photoreduced Form,
Reduced Form at pH 7

 

 

2FWE
2FWF
2FWG
2FWH

 

Stirnimann, C.U., et al.,
J.Mol.Biol. v358 pp.829-845
(2006)

 

2FWE
2FWF
2FWG
2FWH

Crystal Structure Of Apple ACC Synthase In Complex With L-Vinylglycine

 

 

1YNU

 

Capitani, G., et al.,
FEBS lett. v579 pp.2458-2462
(2005)

 

1YNU

Crystal Structure Of Aminoglycoside Phosphotransferase APH (3')-IIIA In Complex With The Inhibitor AR_3A

 

 

2BKK

 

Kohl, A., et al.,
Structure v13 pp.1131-1141
(2005)

 

2BKK

Crystal Structure Of The Ternary Complex of FIMD (N-Terminal Domain) With FIMC and The Pilin Domain Of FIMH

 

 

1ZE3

 

Nishiyama, M., et al.,
Embo J. v24 pp.2075-2086
(2005)

 

1ZE3

Crystal Structure Of The Disulfide-Linked Complex Between The N-Terminal Domain Of The Electron Transfer Catalyst DsbD And The Cytochrome C Biogenesis Protein CcmG

 

 

1Z5Y

 

Stirnimann, C.U., et al.,
Structure v13 pp.985-993
(2005)

 

1Z5Y

Crystal Structure Of A Designed Selected Ankyrin Repeat Protein In Complex With The Maltose Binding Protein

 

 

1SVX

 

Binz, H.K., et al.,
Nat.Biotechnol. v22 pp.575-582
(2004)

 

1SVX

Helicobacter pylori Cysteine Rich Protein C (HcpC)

 

 

1OUV

 

Lüthy L. et al.,
J.Mol.Biol. v340 pp.829-841
(2004)

 

1OUV

Crystal Structure Of The Disulfide-Linked Complex Between The N-Terminal And C-terminal Domain Of The Electron Transfer Catalyst DsbD

 

 

1VRS

 

Rozhkova, A., et al.,
Embo J. v23 pp.1709-1719
(2004)

 

1VRS

Crystal Structures Of Escherichia coli GadB At Neutral And Low pH

 

 

1PMO
1PMM

 

Capitani G. et al.,
EMBO J. v22 pp.4027-4037
(2003)

 

1PMO
1PMM

Crystal Structure Of Apple ACC Synthase In Complex With [2-(Amino-Oxy)Ethyl](5'-DeoxyAdenosin-5'-YL)(Methyl)Sulfonium

 

 

1M4N

 

Capitani, G., et al.,
Biochem.Biophys.Acta Proteins and Proteomics v1647 pp.55-60
(2003)

 

1M4N

Crystal Structure Of A Mycobacterial Hsp60 Epitope With The Murine Class I MHC Molecule H-2Db

 

 

1N3N

 

Ciatto, C., et al.,
FEBS Lett. v543 pp.11-15
(2003)

 

1N3N

Crystal Structure Of The Rabbit Muscle Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)

 

 

1J0X

 

Cowan-Jacob, S.W., et al.,
Acta Crystallogr., Sect.D v59 pp.2218-2227
(2003)

 

1J0X

Crystal Structure Of The Mammalian Tumor Associated Antigen UK114

 

 

1NQ3

 

Deriu D. et al.,
Acta Crystallogr., Sect.D 59:1676-1678
(2003)

 

1NQ3

NMR Structure Of The NALP1 Pyrin Domain (PYD)

 

 

1PN5

 

Hiller, S., et al.,
Structure v11 pp.1199-1205
(2003)

 

1PN5

SANK E3_5: An Artificial Ankyrin Repeat Protein

 

 

1MJ0

 

Kohl, A., et al.,
Proc.Natl.Acad.Sci.USA v100 pp.1700-1705
(2003)

 

1MJ0

Crystal Structure Of Human Caspase-2 In Complex With Acetyl-Leu-Asp-Glu-Ser-Asp-cho

 

 

1PYO

 

Schweizer A. et al.,
J. Biol. Chem. v278 pp.42441-42447
(2003)

 

1PYO

Crystal Structure Of Apple ACC Synthase In Complex With L-aminoethoxyvinylglycine

 

 

1M7Y

 

Capitani G. et al.,
J. Biol. Chem. v277 pp.49735-49742
(2002)

 

1M7Y

Crystal Structure Of Aspergillus fumigatus MnSOD

 

 

1KKC

 

Fluckiger, S., et al.,
J.Immunol. v168 pp.1267-1272
(2002)

 

1KKC

Crystal Structure Of The Anti-His Tag Antibody 3D5 Single-Chain Fragment (scFv) In Complex With A Oligohistidine Peptide

 

 

1KTR

 

Kaufmann M. et al.,
J. Mol. Biol. v18 pp.135-147
(2002)

 

1KTR

Helicobacter pylori Cysteine Rich Protein B (hcpB)

 

 

1KLX

 

Lüthy et al.,
J. Biol. Chem. v277 pp.10187-10193
(2002)

 

1KLX

Crystal Structure Of APO S100A3

 

 

1KSO

 

Mittl et al.,
Acta Crystallogr. Sect.D v58 pp.1255-1261
(2002)

 

1KSO

Crystal Structure Of Mouse Neuroserpin (Cleaved Form)

 

 

1JJO

 

Briand, C.,et al.,
FEBS Lett. v505 pp.18-22
(2001)

 

1JJO

Crystal structure of the soluble domain of TLPA from Bradyrhizobium japonicum

 

 

1JFU

 

Capitani G., et al.,
J. Mol. Biol. v311 pp.1037-1048
(2001)

 

1JFU

Crystal Structures Of The LCMV Peptidic Epitope Gp276 And Of The LCMV Peptidic Epitope Np396 In Complex With The Murine Class I Mhc Molecule H-2Db

 

 

1JPF
1JPG

 

Ciatto, C., et al.,
J.Mol.Biol. v312 pp.1059-1071
(2001)

 

1JPF
1JPG

Caspase-8 Specificity Probed At Subsite S4: Crystal Structure Of The Caspase-8-Z-DEVD-CHO

 

 

1F9E

 

Blanchard, H., et al.,
J.Mol.Biol. v302 pp.9-16
(2000)

 

1F9E

Reversing The Sequence Of The GCN4 Leucine Zipper Does Not Affect Its Fold

 

 

1C94

 

Mittl, P.R., et al.,
Proc.Natl.Acad.Sci.USA. v97 pp.2562-2566
(2000)

 

1C94

Crystal Structure Of The LCMV Peptidic Epitope Gp33 In Complex With The Murine Class I Mhc Molecule H-2Db

 

 

1FG2

 

Tissot, A.C., et al.,
J.Mol.Biol. v302 pp.873-885
(2000)

 

1FG2

Crystal Structure Of The Complex Of Caspase-8 With The Tripeptide Ketone Inhibitor ZEVD-DCBMK

 

 

1QDU

 

Blanchard, H., et al.,
Structure Fold.Des. v7 pp.1125-1133
(1999)

 

1QDU

Updated by C.B. 11/01/2010