The department infrastructure is excellent for biochemical and macromolecular structure studies and there is a general attitude to share equipment and skills among the groups of the department. Our group is equiped with all tools that are nowadays needed to perform state-of-the-art biochemistry and macromolecular crystallography studies including the required infrastructure for eucaryotic and bacterial cell cultures, molecular biology and protein purification.

Biochemistry

• Aekta Purifiers (3), Aekta Primes and HPLC systems (2) for protein purification / protein analysis
• several centrifuges (Herolab HiCen XL, Haereus Biofuge, Bekman, etc.)
• PCR Machines
• shaker for culture flasks (Kühner ISF-1-W)
• Varian Cary 50 scan UV/Vis spectrophotometer
• Nanodrop UV/Vis spectrophotometer
• Dynapro dynamic light scattering
• Analytical Ultracentrifuge ProteomeLab XL-I Beckman
• Cell lab culture fully equiped

Crystallization

• Pipetting robots (2)
• Nano-drop crystallization robots (2) (Cartesian technologies)
• Crystallization plate hotels (2) (Discovery Partners)
• Stereo microscopes (3) (Leica GZ4)

X-ray data collection

• Nonius FR591 X-ray generator equiped with Osmic mirrors, Mar 345-dtb image plate system and Oxford Cryostream (700 series)
• Nonius FR571 X-ray generator equipped with ProPhysiscs XRM-216 mirrors, Mar 345-dtb image plate and Oxford Cryostream (700 series)
• Access to synchrotrons ESRF (Grenoble), DESY (Hamburg) and Swiss Light Source (PSI, Villigen)

Computing

• PC workstations equiped with Stereo Glasses and Dial Box under Linux
• Cluster of linux PCs for running jobs in parallel
• Windows PCs
• The Protein Analysis Unit provides services in the field of DNA sequencing, protein mass-spectrometry and protein sequencing.