Introduction Numbering Sequences Structures Modelling Macros Publications Links
Framework 1 CDR 1 Framework 2 CDR 2 Framework 3a Framework 3b CDR 3 Framework 4

Residues 78-93:

The Framework 3a Region

The "outer" loop, sometimes called CDR 4 in T-cell receptors, contains a two-residue gap in VL (L74, L75, between Kabat L68 and L69). VH and Va have no gap, while Vb has a one-residue gap in position B86 ). This places the second cysteine residue in position 106 (Kabat L88, H92, A90, B92, C94 and D88, IMGT 104)

Click on the pictures for an enlarged and annotated image

AAAAA Homepage Zürich University Dept. of Biochemistry Plückthun Group Annemarie Honegger

Last Modified by A.Honegger Wednesday, July 11, 2001