Publications of the Dutzler Group

ZORA Publication List

Publications

• 2019

  • Manatschal, Cristina; Pujol-Giménez, Jonai; Poirier, Marion; Reymond, Jean-Louis; Hediger, Matthias A; Dutzler, Raimund (2019). Mechanistic basis of the inhibition of SLC11/NRAMP-mediated metal ion transport by bis-isothiourea substituted compounds. eLife, 8:e51913.
  • Walter, Justin D; Sawicka, Marta; Dutzler, Raimund (2019). Cryo-EM structures and functional characterization of murine Slc26a9 reveal mechanism of uncoupled chloride transport. eLife, 8:e46986.
  • Kalienkova, Valeria; Clerico Mosina, Vanessa; Bryner, Laura; Oostergetel, Gert T; Dutzler, Raimund; Paulino, Cristina (2019). Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM. eLife, 8:e44364.
  • Alvadia, Carolina; Lim, Novandy K; Clerico Mosina, Vanessa; Oostergetel, Gert T; Dutzler, Raimund; Paulino, Cristina (2019). Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F. eLife, 8:e44365.

• 2018

  • Lam, Andy K M; Dutzler, Raimund (2018). Calcium-dependent electrostatic control of anion access to the pore of the calcium-activated chloride channel TMEM16A. eLife, 7:39122.
  • Deneka, Dawid; Sawicka, Marta; Lam, Andy K M; Paulino, Cristina; Dutzler, Raimund (2018). Structure of a volume-regulated anion channel of the LRRC8 family. Nature, 558(7709):254-259.

• 2017

  • Paulino, Cristina; Kalienkova, Valeria; Lam, Andy K M; Neldner, Yvonne; Dutzler, Raimund (2017). Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM. Nature, 552(7685):421-425.
  • Schenck, Stephan; Kunz, Laura; Sahlender, Daniela; Pardon, Els; Geertsma, Eric R; Savtchouk, Iaroslav; Suzuki, Toshiharu; Neldner, Yvonne; Štefanić, Saša; Steyaert, Jan; Volterra, Andrea; Dutzler, Raimund (2017). Generation and characterization of Anti-VGLUT nanobodies acting as inhibitors of transport. Biochemistry, 56(30):3962-3971.
  • Paulino, Cristina; Neldner, Yvonne; Lam, Andy K M; Kalienkova, Valeria; Brunner, Janine Denise; Schenck, Stephan; Dutzler, Raimund (2017). Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A. eLife, 6:26232.
  • Ehrnstorfer, Ines A; Manatschal, Cristina; Arnold, Fabian M; Laederach, Juerg; Dutzler, Raimund (2017). Structural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family. Nature Communications, 8:14033.

• 2016

  • Brunner, Janine D; Schenck, Stephan; Dutzler, Raimund (2016). Structural basis for phospholipid scrambling in the TMEM16 family. Current Opinion in Structural Biology, 39:61-70.
  • Geertsma, Eric R; Chang, Yung-Ning; Shaik, Farooque R; Neldner, Yvonne; Pardon, Els; Steyaert, Jan; Dutzler, Raimund (2016). Corrigendum: Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family. Nature Structural & Molecular Biology, 23(5):462.
  • Bertozzi, Carlo; Zimmermann, Iwan; Engeler, Sibylle; Hilf, Ricarda J C; Dutzler, Raimund (2016). Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels. PLoS Biology, 14(3):e1002393.
  • Lim, Novandy K; Lam, Andy K M; Dutzler, Raimund (2016). Independent activation of ion conduction pores in the double-barreled calcium-activated chloride channel TMEM16A. Journal of General Physiology, 148(5):375-392.

• 2015

  • Geertsma, Eric R; Chang, Yung-Ning; Shaik, Farooque R; Neldner, Yvonne; Pardon, Els; Steyaert, Jan; Dutzler, Raimund (2015). Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family. Nature Structural & Molecular Biology, 22(10):803-808.

• 2014

  • Brunner, Janine D; Lim, Novandy K; Schenck, Stephan; Duerst, Alessia; Dutzler, Raimund (2014). X-ray structure of a calcium-activated TMEM16 lipid scramblase. Nature, 516(7530):207-212.
  • Ehrnstorfer, Ines A; Geertsma, Eric R; Pardon, Els; Steyaert, Jan; Dutzler, Raimund (2014). Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport. Nature Structural & Molecular Biology, 21(11):990-996.

• 2013

  • Garcia-Celma, Juan; Szydelko, Adrian; Dutzler, Raimund (2013). Functional characterization of a ClC transporter by solid-supported membrane electrophysiology. Journal of General Physiology, 141(4):479-491.

• 2012

  • Zimmermann, Iwan; Marabelli, Alessandro; Bertozzi, Carlo; Sivilotti, Lucia G; Dutzler, Raimund (2012). Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent Cations. PLoS Biology, 10(11):e1001429.

• 2011

  • Zimmermann, I; Dutzler, R (2011). Ligand activation of the prokaryotic pentameric ligand-gated ion channel ELIC. PLoS Biology, 9(6):e1001101.
  • Geertsma, E R; Dutzler, R (2011). A versatile and efficient high-throughput cloning tool for structural biology. Biochemistry, 50(15):3272-3278.

Pagination