Publications of the Jinek Group

ZORA Publication List

Publications

• 2022

  • Schmitz, Michael; Querques, Irma; Oberli, Seraina; Chanez, Christelle; Jinek, Martin (2022). Structural basis for the assembly of the type V CRISPR-associated transposon complex Cell, 185(26):4999-5010.e17.
  • Pacesa, Martin; Lin, Chun-Han; Cléry, Antoine; Saha, Aakash; Arantes, Pablo R; Bargsten, Katja; Irby, Matthew J; Allain, Frédéric H-T; Palermo, Giulia; Cameron, Peter; Donohoue, Paul D; Jinek, Martin (2022). Structural basis for Cas9 off-target activity Cell, 185(22):4067-4081.e21.
  • Nierzwicki, Łukasz; East, Kyle W; Binz, Jonas M; Hsu, Rohaine V; Ahsan, Mohd; Arantes, Pablo R; Skeens, Erin; Pacesa, Martin; Jinek, Martin; Lisi, George P; Palermo, Giulia (2022). Principles of target DNA cleavage and the role of Mg2+ in the catalysis of CRISPR-Cas9 Nature Catalysis, 5(10):912-922.
  • Muckenfuss, Lena Maria; Migenda Herranz, Anabel Carmen; Boneberg, Franziska Maria; Clerici, Marcello; Jinek, Martin (2022). Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis eLife, 11:e80332.
  • Pacesa, Martin; Loeff, Luuk; Querques, Irma; Muckenfuss, Lena M; Sawicka, Marta; Jinek, Martin (2022). R-loop formation and conformational activation mechanisms of Cas9 Nature, 609(7925):191-196.

• 2021

  • Kroupova, Alena; Ackle, Fabian; Asanović, Igor; Weitzer, Stefan; Boneberg, Franziska M; Faini, Marco; Leitner, Alexander; Chui, Alessia; Aebersold, Ruedi; Martinez, Javier; Jinek, Martin (2021). Molecular architecture of the human tRNA ligase complex eLife, 10:e71656.
  • Querques, Irma; Schmitz, Michael; Oberli, Seraina; Chanez, Christelle; Jinek, Martin (2021). Target site selection and remodelling by type V CRISPR-transposon systems Nature, 599(7885):497-502.
  • Makasheva, Kristina; Bryan, Louise C; Anders, Carolin; Panikulam, Sherin; Jinek, Martin; Fierz, Beat (2021). Multiplexed Single-Molecule Experiments Reveal Nucleosome Invasion Dynamics of the Cas9 Genome Editor Journal of the American Chemical Society, 143(40):16313-16319.
  • Donohoue, Paul D; Pacesa, Martin; Lau, Elaine; Vidal, Bastien; Irby, Matthew J; Nyer, David B; Rotstein, Tomer; Banh, Lynda; Toh, Mckenzi S; Gibson, Jason; Kohrs, Bryan; Baek, Kevin; Owen, Arthur L G; Slorach, Euan M; van Overbeek, Megan; Fuller, Christopher K; May, Andrew P; Jinek, Martin; Cameron, Peter (2021). Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells. Molecular Cell, 81(17):3637-3649.e5.
  • Rothgangl, Tanja; Dennis, Melissa K; Lin, Paulo J C; Oka, Rurika; Witzigmann, Dominik; Villiger, Lukas; Qi, Weihong; Hruzova, Martina; Kissling, Lucas; Lenggenhager, Daniela; Borrelli, Costanza; Egli, Sabina; Frey, Nina; Bakker, Noëlle; Walker, John A; Kadina, Anastasia P; Victorov, Denis V; Pacesa, Martin; Kreutzer, Susanne; Kontarakis, Zacharias; Moor, Andreas; Jinek, Martin; Weissman, Drew; Stoffel, Markus; van Boxtel, Ruben; Holden, Kevin; Pardi, Norbert; Thöny, Beat; Häberle, Johannes; Tam, Ying K; Semple, Sean C; Schwank, Gerald (2021). In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels Nature Biotechnology, 39(8):949-957.
  • Bawankar, Praveen; Lence, Tina; Paolantoni, Chiara; Haussmann, Irmgard U; Kazlauskiene, Migle; Jacob, Dominik; Heidelberger, Jan B; Richter, Florian M; Nallasivan, Mohanakarthik P; Morin, Violeta; Kreim, Nastasja; Beli, Petra; Helm, Mark; Jinek, Martin; Soller, Matthias; Roignant, Jean-Yves (2021). Hakai is required for stabilization of core components of the m6A mRNA methylation machinery Nature Communications, 12:3778.
  • Asanović, Igor; Strandback, Emilia; Kroupova, Alena; et al; Jinek, Martin (2021). The oxidoreductase PYROXD1 uses NAD(P) + as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response Molecular Cell, 81(12):2520-2532.e16.

• 2020

  • Saha, Aakash; Arantes, Pablo R; Hsu, Rohaine V; Narkhede, Yogesh B; Jinek, Martin; Palermo, Giulia (2020). Molecular Dynamics Reveals a DNA-Induced Dynamic Switch Triggering Activation of CRISPR-Cas12a Journal of Chemical Information and Modeling, 60(12):6427-6437.
  • Casalino, Lorenzo; Nierzwicki, Łukasz; Jinek, Martin; Palermo, Giulia (2020). Catalytic Mechanism of Non-Target DNA Cleavage in CRISPR-Cas9 Revealed by Ab Initio Molecular Dynamics ACS Catalysis, 10(22):13596-13605.
  • Pinto, Paola H; Kroupova, Alena; Schleiffer, Alexander; Mechtler, Karl; Jinek, Martin; Weitzer, Stefan; Martinez, Javier (2020). ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity Science, 369(6503):524-530.
  • Wrona, Dominik; Pastukhov, Oleksandr; Pritchard, Robert S; Raimondi, Federica; Tchinda, Joëlle; Jinek, Martin; Siler, Ulrich; Reichenbach, Janine (2020). CRISPR-Directed Therapeutic Correction at the NCF1 Locus Is Challenged by Frequent Incidence of Chromosomal Deletions Molecular Therapy - Methods & Clinical Development, 17:936-943.
  • Davies, Kevin; Jínek, Martin (2020). The CRISPR-RNA World: An Interview with Martin Jínek The CRISPR journal, 3(2):68-72.
  • Garcia-Doval, Carmela; Schwede, Frank; Berk, Christian; Rostøl, Jakob T; Niewoehner, Ole; Tejero, Oliver; Hall, Jonathan; Marraffini, Luciano A; Jinek, Martin (2020). Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6 Nature Communications, 11:1596.

• 2019

  • Jinek, Martin (2019). Uncut but primed for change The CRISPR journal, 2(6):352-354.
  • Allain, Frédéric H-T; Jinek, Martin (2019). Editorial overview: Protein-nucleic acid interactions - cryo-EM, what else?

Pagination