Publications of the Jinek Group

ZORA Publication List

Publications

• 2017

  • Garcia-Doval, C., & Jinek, M. (2017). Molecular architectures and mechanisms of Class 2 CRISPR-associated nucleases Current Opinion in Structural Biology, 47, 157–166. https://doi.org/10.1016/j.sbi.2017.10.015
  • Niewoehner, O., & Jinek, M. (2017). Specialized weaponry: how a type III-A CRISPR-cas system excels at combating phages Cell Host & Microbe, 22, 258–259. https://doi.org/10.1016/j.chom.2017.08.019
  • Niewoehner, O., Garcia-Doval, C., Rostøl, J. T., Berk, C., Schwede, F., Bigler, L., Hall, J., Marraffini, L. A., & Jinek, M. (2017). Type III CRISPR-Cas systems produce cyclic oligoadenylate second messengers Nature, 548, 543–548. https://doi.org/10.1038/nature23467
  • Palermo, G., Miao, Y., Walker, R. C., Jinek, M., & McCammon, J. A. (2017). CRISPR-Cas9 conformational activation as elucidated from enhanced molecular simulations Proceedings of the National Academy of Sciences of the United States of America, 114, 7260–7265. https://doi.org/10.1073/pnas.1707645114
  • Swarts, D. C., van der Oost, J., & Jinek, M. (2017). Structural basis for guide RNA processing and seed-dependent DNA targeting by CRISPR-Cas12a Molecular Cell, 66, 221-233.e4. https://doi.org/10.1016/j.molcel.2017.03.016

• 2016

  • Reimão-Pinto, M. M., Manzenreither, R. A., Burkard, T. R., Sledz, P., Jinek, M., Mechtler, K., & Ameres, S. L. (2016). Molecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila The EMBO Journal, 35, 2417–2434. https://doi.org/10.15252/embj.201695164
  • Lindsay, H., Burger, A., Biyong, B., Felker, A., Hess, C., Zaugg, J., Chiavacci, E., Anders, C., Jinek, M., Mosimann, C., & Robinson, M. D. (2016). CrispRVariants charts the mutation spectrum of genome engineering experiments Nature Biotechnology, 34, 701–702. https://doi.org/10.1038/nbt.3628
  • Burger, A., Lindsay, H., Felker, A., Hess, C., Anders, C., Chiavacci, E., Zaugg, J., Weber, L. M., Catena, R., Jinek, M., Robinson, M. D., & Mosimann, C. (2016). Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes Development, 143, 2025–2037. https://doi.org/10.1242/dev.134809
  • Anders, C., Bargsten, K., & Jinek, M. (2016). Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9 Molecular Cell, 61, 895–902. https://doi.org/10.1016/j.molcel.2016.02.020
  • Niewoehner, O., & Jinek, M. (2016). Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated protein Csm6 RNA, 22, 318–329. https://doi.org/10.1261/rna.054098.115
  • Olieric, V., Weinert, T., Finke, A. D., Anders, C., Li, D., Olieric, N., Borca, C. N., Steinmetz, M. O., Caffrey, M., Jinek, M., & Wang, M. (2016). Data-collection strategy for challenging native SAD phasing Acta Crystallographica. Section D: Structural Biology, 72, 421–429. https://doi.org/10.1107/S2059798315024110
  • Śledź, P., & Jinek, M. (2016). Structural insights into the molecular mechanism of the m(6)A writer complex ELife, 5, 1–16. https://doi.org/10.7554/eLife.18434
  • Palermo, G., Miao, Y., Walker, R. C., Jinek, M., & McCammon, J. A. (2016). Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations ACS Central Science, 2, 756–763. https://doi.org/10.1021/acscentsci.6b00218

• 2015

  • Brandmann, T., & Jinek, M. (2015). Crystal structure of the C-terminal 2’,5’-phosphodiesterase domain of group A rotavirus protein VP3. Proteins, 83, 997–1002. https://doi.org/10.1002/prot.24794
  • Baltimore, D., Berg, P., Botchan, M., Carroll, D., Charo, R. A., Church, G., Corn, J. E., Daley, G. Q., Doudna, J. A., Fenner, M., Greely, H. T., Jinek, M., Martin, G. S., Penhoet, E., Puck, J., Sternberg, S. H., Weissman, J. S., & Yamamoto, K. R. (2015). Biotechnology. A prudent path forward for genomic engineering and germline gene modification Science, 348, 36–38. https://doi.org/10.1126/science.aab1028
  • Anders, C., Niewoehner, O., & Jinek, M. (2015). In Vitro Reconstitution and Crystallization of Cas9 Endonuclease Bound to a Guide RNA and a DNA Target Methods in Enzymology, 558, 515–537. https://doi.org/10.1016/bs.mie.2015.02.008
  • Zou, J., Tran, D., Baalbaki, M., Tang, L. F., Poon, A., Pelonero, A., Titus, E. W., Yuan, C., Shi, C., Patchava, S., Halper, E., Garg, J., Movsesyan, I., Yin, C., Wu, R., Wilsbacher, L. D., Liu, J., Hager, R. L., Coughlin, S. R., … Deo, R. C. (2015). An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish ELife, 4, e09406. https://doi.org/10.7554/eLife.09406

• 2014

  • Anders, C., & Jinek, M. (2014). In vitro enzymology of cas9 Methods in Enzymology, 546, 1–20. https://doi.org/10.1016/B978-0-12-801185-0.00001-5
  • Niewoehner, O., Jinek, M., & Doudna, J. A. (2014). Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases Nucleic Acids Research, 42, 1341–1353. https://doi.org/10.1093/nar/gkt922
  • Anders, C., Niewoehner, O., Duerst, A., & Jinek, M. (2014). Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease Nature, 513, 569–573. https://doi.org/10.1038/nature13579

Pagination