Publications of the Plückthun Group

ZORA Publication List

Publications

• 2015

  • Oude Blenke, E., Klaasse, G., Merten, H., Plückthun, A., Mastrobattista, E., & Martin, N. I. (2015). Liposome functionalization with copper-free “click chemistry.” Journal of Controlled Release, 202, 14–20. https://doi.org/10.1016/j.jconrel.2015.01.027
  • Hillenbrand, M., Schori, C., Schöppe, J., & Plückthun, A. (2015). Comprehensive analysis of heterotrimeric G-protein complex diversity and their interactions with GPCRs in solution Proceedings of the National Academy of Sciences of the United States of America, 112, E1181–E1190. https://doi.org/10.1073/pnas.1417573112
  • Verdurmen, W. P. R., Luginbühl, M., Honegger, A., & Plückthun, A. (2015). Efficient cell-specific uptake of binding proteins into the cytoplasm through engineered modular transport systems Journal of Controlled Release, 200, 13–22. https://doi.org/10.1016/j.jconrel.2014.12.019
  • Bradbury, A., & Plückthun, A. (2015). Reproducibility: Standardize antibodies used in research Nature, 518, 27–29. https://doi.org/10.1038/518027a
  • Goldstein, R., Sosabowski, J., Livanos, M., Leyton, J., Vigor, K., Bhavsar, G., Nagy-Davidescu, G., Rashid, M., Miranda, E., Yeung, J., Tolner, B., Plückthun, A., Mather, S., Meyer, T., & Chester, K. (2015). Development of the designed ankyrin repeat protein (DARPin) G3 for HER2 molecular imaging European Journal of Nuclear Medicine and Molecular Imaging, 42, 288–301. https://doi.org/10.1007/s00259-014-2940-2
  • Salvati Manni, L., Zabara, A., Osornio, Y. M., Schöppe, J., Batyuk, A., Plückthun, A., Siegel, J. S., Mezzenga, R., & Landau, E. M. (2015). Phase behavior of a designed cyclopropyl analogue of monoolein: implications for low-temperature membrane protein crystallization Angewandte Chemie Internationale Edition, 54, 1027–1031. https://doi.org/10.1002/anie.201409791
  • Plückthun, A. (2015). Designed ankyrin repeat proteins (DARPins): binding proteins for research, diagnostics, and therapy Annual Review of Pharmacology and Toxicology, 55, 489–511. https://doi.org/10.1146/annurev-pharmtox-010611-134654
  • Münch, R. C., Muth, A., Muik, A., Friedel, T., Schmatz, J., Dreier, B., Trkola, A., Plückthun, A., Büning, H., & Buchholz, C. J. (2015). Off-target-free gene delivery by affinity-purified receptor-targeted viral vectors Nature Communications, 6, 6246. https://doi.org/10.1038/ncomms7246

• 2014

  • Stefan, N., Zimmermann, M., Simon, M., Zangemeister-Wittke, U., & Plückthun, A. (2014). Novel prodrug-like fusion toxin with protease-sensitive bioorthogonal PEGylation for tumor targeting Bioconjugate Chemistry, 25, 2144–2156. https://doi.org/10.1021/bc500468s
  • Reichen, C., Madhurantakam, C., Plückthun, A., & Mittl, P. R. E. (2014). Crystal structures of designed armadillo repeat proteins: Implications of construct design and crystallization conditions on overall structure Protein Science, 23, 1572–1583. https://doi.org/10.1002/pro.2535
  • Larrick, J. W., Parren, P. W., Huston, J. S., Plückthun, A., Bradbury, A., Tomlinson, I. M., Chester, K. A., Burton, D. R., Adams, G. P., Weiner, L. M., Scott, J. K., Alfenito, M. R., Veldman, T., & Reichert, J. M. (2014). Antibody engineering and therapeutics conference MAbs, 6, 1115–1123. https://doi.org/10.4161/19420862.2014.971627
  • Jost, C., & Plückthun, A. (2014). Engineered proteins with desired specificity: DARPins, other alternative scaffolds and bispecific IgGs Current Opinion in Structural Biology, 27, 102–112. https://doi.org/10.1016/j.sbi.2014.05.011
  • Schilling, J., Schöppe, J., & Plückthun, A. (2014). From DARPins to LoopDARPins: novel LoopDARPin design allows the selection of low picomolar binders in a single round of ribosome display Journal of Molecular Biology, 426, 691–721. https://doi.org/10.1016/j.jmb.2013.10.026
  • Reichen, C., Hansen, S., & Plückthun, A. (2014). Modular peptide binding: from a comparison of natural binders to designed armadillo repeat proteins Journal of Structural Biology, 185, 147–162. https://doi.org/10.1016/j.jsb.2013.07.012
  • Scholz, O., Hansen, S., & Plückthun, A. (2014). G-quadruplexes are specifically recognized and distinguished by selected designed ankyrin repeat proteins Nucleic Acids Research, 42, 9182–9194. https://doi.org/10.1093/nar/gku571
  • Schilling, J., Schöppe, J., Sauer, E., & Plückthun, A. (2014). Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W Journal of Molecular Biology, 426, 2346–2362. https://doi.org/10.1016/j.jmb.2014.04.010
  • Simon, M., Stefan, N., Borsig, L., Plückthun, A., & Zangemeister-Wittke, U. (2014). Increasing the antitumor effect of an EpCAM-targeting fusion toxin by facile click PEGylation Molecular Cancer Therapeutics, 13, 375–385. https://doi.org/10.1158/1535-7163.MCT-13-0523
  • Scott, D. J., Kummer, L., Egloff, P., Bathgate, R. A. D., & Plückthun, A. (2014). Improving the apo-state detergent stability of NTS1 with CHESS for pharmacological and structural studies Biochimica et Biophysica Acta, 1838, 2817–2824. https://doi.org/10.1016/j.bbamem.2014.07.015
  • Yan, J., Gu, G. J., Jost, C., Hammond, M., Plückthun, A., Landegren, U., & Kamali-Moghaddam, M. (2014). A universal approach to prepare reagents for DNA-assisted protein analysis PLoS ONE, 9, e108061. https://doi.org/10.1371/journal.pone.0108061
  • Brauchle, M., Hansen, S., Caussinus, E., Lenard, A., Ochoa-Espinosa, A., Scholz, O., Sprecher, S. G., Plückthun, A., & Affolter, M. (2014). Protein interference applications in cellular and developmental biology using DARPins that recognize GFP and mCherry Biology Open, 3, 1252–1261. https://doi.org/10.1242/bio.201410041

Pagination