Publications of the Plückthun Group

ZORA Publication List

Publications

• 2014

  • Egloff, P., Hillenbrand, M., Klenk, C., Batyuk, A., Heine, P., Balada, S., Schlinkmann, K. M., Scott, D. J., Schütz, M., & Plückthun, A. (2014). Structure of signaling-competent neurotensin receptor 1 obtained by directed evolution in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America, 111, E655–E662. https://doi.org/10.1073/pnas.1317903111
  • Watson, R. P., Christen, M. T., Ewald, C., Bumbak, F., Reichen, C., Mihajlovic, M., Schmidt, E., Güntert, P., Caflisch, A., Plückthun, A., & Zerbe, O. (2014). Spontaneous self-assembly of engineered armadillo repeat protein fragments into a folded structure Structure, 22, 985–995. https://doi.org/10.1016/j.str.2014.05.002
  • Hanenberg, M., McAfoose, J., Kulic, L., Welt, T., Wirth, F., Parizek, P., Strobel, L., Cattepoel, S., Späni, C., Derungs, R., Maier, M., Plückthun, A., & Nitsch, R. M. (2014). Amyloid-β peptide-specific DARPins as a novel class of potential therapeutics for Alzheimer disease Journal of Biological Chemistry, 289, 27080–27089. https://doi.org/10.1074/jbc.M114.564013
  • Kiuchi, T., Ortiz-Zapater, E., Monypenny, J., Matthews, D. R., Nguyen, L. K., Barbeau, J., Coban, O., Lawler, K., Burford, B., Rolfe, D. J., de Rinaldis, E., Dafou, D., Simpson, M. A., Woodman, N., Pinder, S., Gillett, C. E., Devauges, V., Poland, S. P., Fruhwirth, G., … Ng, T. (2014). The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility Science Signaling, 7, ra78. https://doi.org/10.1126/scisignal.2005157

• 2013

  • Scott, D. J., & Plückthun, A. (2013). Direct molecular evolution of detergent-stable G protein-coupled receptors using polymer encapsulated cells Journal of Molecular Biology, 425, 662–677. https://doi.org/10.1016/j.jmb.2012.11.015
  • Simon, M., Frey, R., Zangemeister-Wittke, U., & Plückthun, A. (2013). Orthogonal assembly of a designed ankyrin repeat protein-cytotoxin conjugate with a clickable serum albumin module for half-life extension Bioconjugate Chemistry, 24, 1955–1966. https://doi.org/10.1021/bc4004102
  • Scott, D. J., Kummer, L., Tremmel, D., & Plückthun, A. (2013). Stabilizing membrane proteins through protein engineering Current Opinion in Chemical Biology, 17, 427–435. https://doi.org/10.1016/j.cbpa.2013.04.002
  • Simon, M., Stefan, N., Plückthun, A., & Zangemeister-Wittke, U. (2013). Epithelial cell adhesion molecule-targeted drug delivery for cancer therapy Expert Opinion on Drug Delivery, 10, 451–468. https://doi.org/10.1517/17425247.2013.759938
  • Jost, C., Schilling, J., Tamaskovic, R., Schwill, M., Honegger, A., & Plückthun, A. (2013). Structural basis for eliciting a cytotoxic effect in HER2-overexpressing cancer cells via binding to the extracellular domain of HER2 Structure, 21, 1979–1991. https://doi.org/10.1016/j.str.2013.08.020
  • Gigant, B., Wang, W., Dreier, B., Jiang, Q., Pecqueur, L., Plückthun, A., Wang, C., & Knossow, M. (2013). Structure of a kinesin-tubulin complex and implications for kinesin motility Nature Structural & Molecular Biology, 20, 1001–1007. https://doi.org/10.1038/nsmb.2624
  • Epa, V. C., Dolezal, O., Doughty, L., Xiao, X., Jost, C., Plückthun, A., & Adams, T. E. (2013). Structural model for the interaction of a designed Ankyrin Repeat Protein with the human epidermal growth factor receptor 2 PLoS ONE, 8, e59163. https://doi.org/10.1371/journal.pone.0059163
  • Gu, G. J., Friedman, M., Jost, C., Johnsson, K., Kamali-Moghaddam, M., Plückthun, A., Landegren, U., & Söderberg, O. (2013). Protein tag-mediated conjugation of oligonucleotides to recombinant affinity binders for proximity ligation New Biotechnology, 30, 144–152. https://doi.org/10.1016/j.nbt.2012.05.005
  • Kummer, L., Hsu, C.-W., Dagliyan, O., Macnevin, C., Kaufholz, M., Zimmermann, B., Dokholyan, N. V., Hahn, K. M., & Plückthun, A. (2013). Knowledge-based design of a biosensor to quantify localized ERK activation in living cells Chemistry & Biology, 20, 847–856. https://doi.org/10.1016/j.chembiol.2013.04.016
  • Dreier, B., Honegger, A., Hess, C., Nagy-Davidescu, G., Mittl, P. R. E., Grütter, M. G., Belousova, N., Mikheeva, G., Krasnykh, V., & Plückthun, A. (2013). Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters Proceedings of the National Academy of Sciences of the United States of America, 110, E869–E877. https://doi.org/10.1073/pnas.1213653110
  • Mann, A., Friedrich, N., Krarup, A., Weber, J., Stiegeler, E., Dreier, B., Pugach, P., Robbiani, M., Riedel, T., Moehle, K., Robinson, J. A., Rusert, P., Plückthun, A., & Trkola, A. (2013). Conformation-dependent recognition of HIV gp120 by designed ankyrin repeat proteins provides access to novel HIV entry inhibitors Journal of Virology, 87, 5868–5881. https://doi.org/10.1128/JVI.00152-13
  • Friedrich, K., Hanauer, J. R. H., Prüfer, S., Münch, R. C., Völker, I., Filippis, C., Jost, C., Hanschmann, K.-M., Cattaneo, R., Peng, K.-W., Plückthun, A., Buchholz, C. J., Cichutek, K., & Mühlebach, M. D. (2013). DARPin-targeting of measles virus: unique bispecificity, effective oncolysis, and enhanced safety Molecular Therapy, 21, 849–859. https://doi.org/10.1038/mt.2013.16

• 2012

  • Frei, A. P., Jeon, O.-Y., Kilcher, S., Moest, H., Henning, L. M., Jost, C., Plückthun, A., Mercer, J., Aebersold, R., Carreira, E. M., & Wollscheid, B. (2012). Direct identification of ligand-receptor interactions on living cells and tissues Nature Biotechnology, 30, 997–1001. https://doi.org/10.1038/nbt.2354
  • Plückthun, A. (2012). Ribosome Display: A Perspective Ribosome Display and Related Technologies, 805, 3–28. https://doi.org/10.1007/978-1-61779-379-0_1
  • Dreier, B., & Plückthun, A. (2012). Rapid selection of high-affinity binders using ribosome display Ribosome Display and Related Technologies, 805, 261–286. https://doi.org/10.1007/978-1-61779-379-0_15
  • Schaefer, J. V., & Plückthun, A. (2012). Engineering aggregation resistance in IgG by two independent mechanisms: lessons from comparison of Pichia pastoris and mammalian cell expression Journal of Molecular Biology, 417, 309–335. https://doi.org/10.1016/j.jmb.2012.01.027

Pagination