Publications of the Plückthun Group

ZORA Publication List

Publications

• 2023

  • Freitag, P. C., Kaulfuss, M., Flühler, L., Mietz, J., Weiss, F., Brücher, D., Kolibius, J., Hartmann, K. P., Smith, S. N., Münz, C., Chijioke, O., & Plückthun, A. (2023). Targeted adenovirus-mediated transduction of human T cells in vitro and in vivo Molecular Therapy - Methods & Clinical Development, 29, 120–132. https://doi.org/10.1016/j.omtm.2023.02.012
  • Becker, L., & Plückthun, A. (2023). DARPins bind their cytosolic targets after having been translocated through the protective antigen pore of anthrax toxin Scientific Reports, 13, 8048. https://doi.org/10.1038/s41598-023-34647-1
  • Gut, M., Dreier, B., Furler, S., Sobek, J., Plückthun, A., & Holland, J. P. (2023). Designed ankyrin repeat proteins for detecting prostate-specific antigen expression in vivo RSC Chemical Biology, 4, 494–505. https://doi.org/10.1039/d3cb00010a
  • Blanc, M., Lettl, C., Guérin, J., Vieille, A., Furler, S., Briand-Schumacher, S., Dreier, B., Bergé, C., Plückthun, A., Vadon-Le Goff, S., Fronzes, R., Rousselle, P., Fischer, W., & Terradot, L. (2023). Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system PLoS Pathogens, 19, e1011368. https://doi.org/10.1371/journal.ppat.1011368
  • Schubert, R., Bae, T., Simic, B., Smith, S. N., Park, S.-H., Nagy-Davidescu, G., Gradinaru, V., Plückthun, A., & Hur, J. K. (2023). CRISPR-clear imaging of melanin-rich B16-derived solid tumors Communications Biology, 6, 370. https://doi.org/10.1038/s42003-023-04614-7
  • Klenk, C., Scrivens, M., Niederer, A., Shi, S., Mueller, L., Gersz, E., Zauderer, M., Smith, E. S., Strohner, R., & Plückthun, A. (2023). A Vaccinia-based system for directed evolution of GPCRs in mammalian cells Nature Communications, 14, 1770. https://doi.org/10.1038/s41467-023-37191-8
  • Schellhorn, S., Brücher, D., Wolff, N. A., Schröer, K., Sallard, E., Mese, K., Zhang, W., Ehrke-Schulz, E., Thévenod, F., Plückthun, A., & Ehrhardt, A. (2023). Targeting Oncolytic Adenoviruses to Cancer Cells Using a Designed Ankyrin Repeat Protein Lipocalin-2 Fusion Protein Human Gene Therapy, 34, 203–216. https://doi.org/10.1089/hum.2022.215
  • Michel, E., Cucuzza, S., Mittl, P. R. E., Zerbe, O., & Plückthun, A. (2023). Improved Repeat Protein Stability by Combined Consensus and Computational Protein Design Biochemistry, 62, 318–329. https://doi.org/10.1021/acs.biochem.2c00083

• 2022

  • Strubel, A., Münick, P., Chaikuad, A., Dreier, B., Schaefer, J., Gebel, J., Osterburg, C., Tuppi, M., Schäfer, B., Knapp, S., Plückthun, A., & Dötsch, V. (2022). Designed Ankyrin Repeat Proteins as a tool box for analyzing p63 Cell Death and Differentiation, 29, 2445–2458. https://doi.org/10.1038/s41418-022-01030-y
  • Kiss, C., Gall, F. M., Dreier, B., Adams, M., Riedl, R., Plückthun, A., & Mittl, P. R. E. (2022). Structure of a hydrophobic leucinostatin derivative determined by host lattice display Acta Crystallographica. Section D: Structural Biology, 78, 1439–1450. https://doi.org/10.1107/S2059798322010762
  • Philippi, M., Richter, C. P., Kappen, M., Watrinet, I., Miao, Y., Runge, M., Jorde, L., Korneev, S., Holtmannspötter, M., Kurre, R., Holthuis, J. C. M., Garcia, K. C., Plückthun, A., Steinhart, M., Piehler, J., & You, C. (2022). Biofunctional Nanodot Arrays in Living Cells Uncover Synergistic Co-Condensation of Wnt Signalodroplets Small, 18, 2203723. https://doi.org/10.1002/smll.202203723
  • Campbell, B. F. N., Dittmann, A., Dreier, B., Plückthun, A., & Tyagarajan, S. K. (2022). A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology ELife, 11, e80895. https://doi.org/10.7554/eLife.80895
  • Fay, R., Törő, I., Schinke, A.-L., Simic, B., Schaefer, J. V., Dreier, B., Plückthun, A., & Holland, J. P. (2022). Sortase-Mediated Site-Specific Conjugation and 89Zr-Radiolabeling of Designed Ankyrin Repeat Proteins for PET Molecular Pharmaceutics, 19, 3576–3585. https://doi.org/10.1021/acs.molpharmaceut.2c00136
  • Strittmatter, T., Wang, Y., Bertschi, A., Scheller, L., Freitag, P. C., Ray, P. G., Stuecheli, P., Schaefer, J. V., Reinberg, T., Tsakiris, D., Plückthun, A., Ye, H., & Fussenegger, M. (2022). Programmable DARPin-based receptors for the detection of thrombotic markers Nature Chemical Biology, 18, 1125–1134. https://doi.org/10.1038/s41589-022-01095-3
  • Zhang, Y., Wang, Y., Uslu, S., Venkatachalapathy, S., Rashidian, M., Schaefer, J. V., Plückthun, A., & Distefano, M. D. (2022). Enzymatic Construction of DARPin-Based Targeted Delivery Systems Using Protein Farnesyltransferase and a Capture and Release Strategy International Journal of Molecular Sciences, 23, 11537. https://doi.org/10.3390/ijms231911537
  • Freitag, P. C., Brandl, F., Brücher, D., Weiss, F., Dreier, B., & Plückthun, A. (2022). Modular Adapters Utilizing Binders of Different Molecular Types Expand Cell-Targeting Options for Adenovirus Gene Delivery Bioconjugate Chemistry, 33, 1595–1601. https://doi.org/10.1021/acs.bioconjchem.2c00346
  • Waltenspühl, Y., Ehrenmann, J., Vacca, S., Thom, C., Medalia, O., & Plückthun, A. (2022). Structural basis for the activation and ligand recognition of the human oxytocin receptor Nature Communications, 13, 4153. https://doi.org/10.1038/s41467-022-31325-0
  • Kirchhammer, N., Trefny, M. P., Natoli, M., Brücher, D., Smith, S. N., Werner, F., Koch, V., Schreiner, D., Bartoszek, E., Buchi, M., Schmid, M., Breu, D., Hartmann, K. P., Zaytseva, P., Thommen, D. S., Läubli, H., Böttcher, J. P., Stanczak, M. A., Kashyap, A. S., … Zippelius, A. (2022). NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity Science Translational Medicine, 14, eabm9043. https://doi.org/10.1126/scitranslmed.abm9043
  • Kopra, K., Valtonen, S., Mahran, R., Kapp, J. N., Hassan, N., Gillette, W., Dennis, B., Li, L., Westover, K. D., Plückthun, A., & Härmä, H. (2022). Thermal Shift Assay for Small GTPase Stability Screening: Evaluation and Suitability International Journal of Molecular Sciences, 23, 7095. https://doi.org/10.3390/ijms23137095
  • Guimaraes Koch, S. S., Thorpe, R., Kawasaki, N., Lefranc, M.-P., Malan, S., Martin, A. C. R., Mignot, G., Plückthun, A., Rizzi, M., Shubat, S., Weisser, K., & Balocco, R. (2022). International nonproprietary names for monoclonal antibodies: an evolving nomenclature system MAbs, 14, 2075078. https://doi.org/10.1080/19420862.2022.2075078

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