Publications of the Plückthun Group

ZORA Publication List

Publications

• 2022

  • Qi, C., Lavriha, P., Mehta, V., Khanppnavar, B., Mohammed, I., Li, Y., Lazaratos, M., Schaefer, J. V., Dreier, B., Plückthun, A., Bondar, A.-N., Dessauer, C. W., & Korkhov, V. M. (2022). Structural basis of adenylyl cyclase 9 activation Nature Communications, 13, 1045. https://doi.org/10.1038/s41467-022-28685-y
  • Deluigi, M., Morstein, L., Schuster, M., Klenk, C., Merklinger, L., Cridge, R. R., de Zhang, L. A., Klipp, A., Vacca, S., Vaid, T. M., Mittl, P. R. E., Egloff, P., Eberle, S. A., Zerbe, O., Chalmers, D. K., Scott, D. J., & Plückthun, A. (2022). Crystal structure of the α$_{1B}$-adrenergic receptor reveals molecular determinants of selective ligand recognition Nature Communications, 13, 382. https://doi.org/10.1038/s41467-021-27911-3
  • Matsuda, S., Schaefer, J. V., Mii, Y., Hori, Y., Bieli, D., Taira, M., Plückthun, A., & Affolter, M. (2022). Author Correction: Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc Nature Communications, 13, 389. https://doi.org/10.1038/s41467-021-27680-z

• 2021

  • Bieri, M., Hendrickx, R., Bauer, M., Yu, B., Jetzer, T., Dreier, B., Mittl, P. R. E., Sobek, J., Plückthun, A., Greber, U. F., & Hemmi, S. (2021). The RGD-binding integrins αvβ6 and αvβ8 are receptors for mouse adenovirus-1 and -3 infection PLoS Pathogens, 17, e1010083. https://doi.org/10.1371/journal.ppat.1010083
  • Thom, C., Ehrenmann, J., Vacca, S., Waltenspühl, Y., Schöppe, J., Medalia, O., & Plückthun, A. (2021). Structures of neurokinin 1 receptor in complex with Gq and Gs proteins reveal substance P binding mode and unique activation features Science Advances, 7, eabk2872. https://doi.org/10.1126/sciadv.abk2872
  • Bradbury, A. R. M., Dübel, S., Knappik, A., & Plückthun, A. (2021). Animal- versus in vitro-derived antibodies: avoiding the extremes MAbs, 13, 1950265. https://doi.org/10.1080/19420862.2021.1950265
  • Cucuzza, S., Güntert, P., Plückthun, A., & Zerbe, O. (2021). Correction to: An automated iterative approach for protein structure refinement using pseudocontact shifts Journal of Biomolecular NMR, 75, 429–430. https://doi.org/10.1007/s10858-021-00378-6
  • Friedrich, N., Stiegeler, E., Glögl, M., Lemmin, T., Hansen, S., Kadelka, C., Wu, Y., Ernst, P., Maliqi, L., Foulkes, C., Morin, M., Eroglu, M., Liechti, T., Ivan, B., Reinberg, T., Schaefer, J. V., Karakus, U., Ursprung, S., Mann, A., … Trkola, A. (2021). Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization Nature Communications, 12, 6705. https://doi.org/10.1038/s41467-021-27075-0
  • Matsuda, S., Schaefer, J. V., Mii, Y., Hori, Y., Bieli, D., Taira, M., Plückthun, A., & Affolter, M. (2021). Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc Nature Communications, 12, 6435. https://doi.org/10.1038/s41467-021-26726-6
  • Merten, H., Brandl, F., Zimmermann, M., Schaefer, J. V., Irpinio, L., Sand, K. M. K., Nilsen, J., Andersen, J. T., Zangemeister-Wittke, U., & Plückthun, A. (2021). Half-life extension of efficiently produced DARPin serum albumin fusions as a function of FcRn affinity and recycling European Journal of Pharmaceutics and Biopharmaceutics, 167, 104–113. https://doi.org/10.1016/j.ejpb.2021.07.011
  • Mysore, V. P., Zhou, Z.-W., Ambrogio, C., Li, L., Kapp, J. N., Lu, C., Wang, Q., Tucker, M. R., Okoro, J. J., Nagy-Davidescu, G., Bai, X., Plückthun, A., Jänne, P. A., Westover, K. D., Shan, Y., & Shaw, D. E. (2021). A structural model of a Ras-Raf signalosome Nature Structural & Molecular Biology, 28, 847–857. https://doi.org/10.1038/s41594-021-00667-6
  • Nemergut, M., Škrabana, R., Berta, M., Plückthun, A., & Sedlák, E. (2021). Purification of MBP fusion proteins using engineered DARPin affinity matrix International Journal of Biological Macromolecules, 187, 105–112. https://doi.org/10.1016/j.ijbiomac.2021.07.117
  • Stephens, E. A., Ludwicki, M. B., Meksiriporn, B., Li, M., Ye, T., Monticello, C., Forsythe, K. J., Kummer, L., Zhou, P., Plückthun, A., & DeLisa, M. P. (2021). Engineering Single Pan-Specific Ubiquibodies for Targeted Degradation of All Forms of Endogenous ERK Protein Kinase ACS Synthetic Biology, 10, 2396–2408. https://doi.org/10.1021/acssynbio.1c00357
  • Cucuzza, S., Güntert, P., Plückthun, A., & Zerbe, O. (2021). An automated iterative approach for protein structure refinement using pseudocontact shifts Journal of Biomolecular NMR, 75, 319–334. https://doi.org/10.1007/s10858-021-00376-8
  • Kosareva, A., Punjabi, M., Ochoa-Espinosa, A., Xu, L., Schaefer, J. V., Dreier, B., Plückthun, A., & Kaufmann, B. A. (2021). Designed Ankyrin Repeat Proteins as Novel Binders for Ultrasound Molecular Imaging Ultrasound in Medicine & Biology, 47, 2664–2675. https://doi.org/10.1016/j.ultrasmedbio.2021.04.027
  • Becker, L., Singh Badwal, J., Brandl, F., Verdurmen, W. P. R., & Plückthun, A. (2021). Thermodynamic Stability Is a Strong Predictor for the Delivery of DARPins to the Cytosol via Anthrax Toxin Pharmaceutics, 13, 1285. https://doi.org/10.3390/pharmaceutics13081285
  • Radom, F., Vonrhein, C., Mittl, P. R. E., & Plückthun, A. (2021). Crystal structures of HER3 extracellular domain 4 in complex with the designed ankyrin-repeat protein D5 Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 77, 192–201. https://doi.org/10.1107/S2053230X21006002
  • Stüber, J. C., Richter, C. P., Bellón, J. S., Schwill, M., König, I., Schuler, B., Piehler, J., & Plückthun, A. (2021). Apoptosis-inducing anti-HER2 agents operate through oligomerization-induced receptor immobilization Communications Biology, 4, 762. https://doi.org/10.1038/s42003-021-02253-4
  • Kast, F., Schwill, M., Stüber, J. C., Pfundstein, S., Nagy-Davidescu, G., Rodríguez, J. M. M., Seehusen, F., Richter, C. P., Honegger, A., Hartmann, K. P., Weber, T. G., Kroener, F., Ernst, P., Piehler, J., & Plückthun, A. (2021). Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action Nature Communications, 12, 3790. https://doi.org/10.1038/s41467-021-23948-6
  • Hartmann, J., Münch, R. C., Freiling, R.-T., Schneider, I. C., Dreier, B., Samukang, W., Koch, J., Seeger, M. A., Plückthun, A., & Buchholz, C. J. (2021). Erratum: A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors Molecular Therapy - Methods & Clinical Development, 21, 728. https://doi.org/10.1016/j.omtm.2021.05.006

Pagination