Publications of the Plückthun Group

ZORA Publication List

Publications

• 2021

  • Vulovic, I., Yao, Q., Park, Y.-J., Courbet, A., Norris, A., Busch, F., Sahasrabuddhe, A., Merten, H., Sahtoe, D. D., Ueda, G., Fallas, J. A., Weaver, S. J., Hsia, Y., Langan, R. A., Plückthun, A., Wysocki, V. H., Veesler, D., Jensen, G. J., & Baker, D. (2021). Generation of ordered protein assemblies using rigid three-body fusion Proceedings of the National Academy of Sciences of the United States of America, 118, e2015037118. https://doi.org/10.1073/pnas.2015037118
  • Smith, S. N., Schubert, R., Simic, B., Brücher, D., Schmid, M., Kirk, N., Freitag, P. C., Gradinaru, V., & Plückthun, A. (2021). The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody Proceedings of the National Academy of Sciences of the United States of America, 118, e2017925118. https://doi.org/10.1073/pnas.2017925118
  • Incaviglia, I., Frutiger, A., Blickenstorfer, Y., Treindl, F., Ammirati, G., Lüchtefeld, I., Dreier, B., Plückthun, A., Vörös, J., & Reichmuth, A. M. (2021). An Approach for the Real-Time Quantification of Cytosolic Protein-Protein Interactions in Living Cells ACS Sensors, 6, 1572–1582. https://doi.org/10.1021/acssensors.0c02480
  • Waltenspühl, Y., Jeliazkov, J. R., Kummer, L., & Plückthun, A. (2021). Directed evolution for high functional production and stability of a challenging G protein-coupled receptor Scientific Reports, 11, 8630. https://doi.org/10.1038/s41598-021-87793-9
  • Waltenspühl, Y., Ehrenmann, J., Klenk, C., & Plückthun, A. (2021). Engineering of Challenging G Protein-Coupled Receptors for Structure Determination and Biophysical Studies Molecules, 26, 1465. https://doi.org/10.3390/molecules26051465
  • Brücher, D., Kirchhammer, N., Smith, S. N., Schumacher, J., Schumacher, N., Kolibius, J., Freitag, P. C., Schmid, M., Weiss, F., Keller, C., Grove, M., Greber, U. F., Zippelius, A., & Plückthun, A. (2021). iMATCH: an integrated modular assembly system for therapeutic combination high-capacity adenovirus gene therapy Molecular Therapy - Methods & Clinical Development, 20, 572–586. https://doi.org/10.1016/j.omtm.2021.01.002
  • Zhang, M., Gui, M., Wang, Z.-F., Gorgulla, C., Yu, J. J., Wu, H., Sun, Z.-Y. J., Klenk, C., Merklinger, L., Morstein, L., Hagn, F., Plückthun, A., Brown, A., Nasr, M. L., & Wagner, G. (2021). Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs Nature Structural & Molecular Biology, 28, 258–267. https://doi.org/10.1038/s41594-020-00554-6
  • Goba, I., Goricanec, D., Schum, D., Hillenbrand, M., Plückthun, A., & Hagn, F. (2021). Probing the Conformation States of Neurotensin Receptor 1 Variants by NMR Site-Directed Methyl Labeling Chembiochem, 22, 139–146. https://doi.org/10.1002/cbic.202000541
  • Teale, W. D., Pasternak, T., Dal Bosco, C., Dovzhenko, A., Kratzat, K., Bildl, W., Schwörer, M., Falk, T., Ruperti, B., Schaefer, J. V., Shahriari, M., Pilgermayer, L., Li, X., Lübben, F., Plückthun, A., Schulte, U., & Palme, K. (2021). Flavonol-mediated stabilization of PIN efflux complexes regulates polar auxin transport The EMBO Journal, 40, e104416. https://doi.org/10.15252/embj.2020104416
  • Deluigi, M., Klipp, A., Klenk, C., Merklinger, L., Eberle, S. A., Morstein, L., Heine, P., Mittl, P. R. E., Ernst, P., Kamenecka, T. M., He, Y., Vacca, S., Egloff, P., Honegger, A., & Plückthun, A. (2021). Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism Science Advances, 7, eabe5504. https://doi.org/10.1126/sciadv.abe5504

• 2020

  • Brandl, F., Busslinger, S., Zangemeister-Wittke, U., & Plückthun, A. (2020). Optimizing the anti-tumor efficacy of protein-drug conjugates by engineering the molecular size and half-life Journal of Controlled Release, 327, 186–197. https://doi.org/10.1016/j.jconrel.2020.08.004
  • Gray, A., Bradbury, A. R. M., Knappik, A., Plückthun, A., Borrebaeck, C. A. K., & Dübel, S. (2020). Animal-free alternatives and the antibody iceberg Nature Biotechnology, 38, 1234–1239. https://doi.org/10.1038/s41587-020-0687-9
  • Nowak, K., Rosenthal, F., Karlberg, T., Bütepage, M., Thorsell, A.-G., Dreier, B., Grossmann, J., Sobek, J., Imhof, R., Lüscher, B., Schüler, H., Plückthun, A., Leslie Pedrioli, D. M., & Hottiger, M. O. (2020). Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins Nature Communications, 11, 5199. https://doi.org/10.1038/s41467-020-18981-w
  • Schuster, M., Deluigi, M., Pantić, M., Vacca, S., Baumann, C., Scott, D. J., Plückthun, A., & Zerbe, O. (2020). Optimizing the α1B-adrenergic receptor for solution NMR studies Biochimica et Biophysica Acta. Biomembranes, 1862, 183354. https://doi.org/10.1016/j.bbamem.2020.183354
  • Becker, L., Verdurmen, W. P. R., & Plückthun, A. (2020). Reengineering anthrax toxin protective antigen for improved receptor-specific protein delivery BMC Biology, 18, 100. https://doi.org/10.1186/s12915-020-00827-y
  • Gray, A. C., Bradbury, A. R. M., Knappik, A., Plückthun, A., Borrebaeck, C. A. K., & Dübel, S. (2020). Animal-derived-antibody generation faces strict reform in accordance with European Union policy on animal use Nature Methods, 17, 755–756. https://doi.org/10.1038/s41592-020-0906-9
  • Brücher, D., Franc, V., Smith, S. N., Heck, A. J. R., & Plückthun, A. (2020). Malignant tissues produce divergent antibody glycosylation of relevance for cancer gene therapy effectiveness MAbs, 12, 1792084. https://doi.org/10.1080/19420862.2020.1792084
  • Chabloz, A., Schaefer, J. V., Kozieradzki, I., Cronin, S. J. F., Strebinger, D., Macaluso, F., Wald, J., Rabbitts, T. H., Plückthun, A., Marlovits, T. C., & Penninger, J. M. (2020). Salmonella-based platform for efficient delivery of functional binding proteins to the cytosol Communications Biology, 3, 342. https://doi.org/10.1038/s42003-020-1072-4
  • Waltenspühl, Y., Schöppe, J., Ehrenmann, J., Kummer, L., & Plückthun, A. (2020). Crystal structure of the human oxytocin receptor Science Advances, 6, eabb5419. https://doi.org/10.1126/sciadv.abb5419
  • Persson, B. D., Lenman, A., Frängsmyr, L., Schmid, M., Ahlm, C., Plückthun, A., Jenssen, H., & Arnberg, N. (2020). Lactoferrin-hexon interactions mediate CAR-independent adenovirus infection of human respiratory cells Journal of Virology, 94, e00542-20. https://doi.org/10.1128/JVI.00542-20

Pagination