Publications of the Plückthun Group

ZORA Publication List

Publications

• 2020

  • Gray, A. C., Bradbury, A., Dübel, S., Knappik, A., Plückthun, A., & Borrebaeck, C. A. K. (2020). Reproducibility: bypass animals for antibody production Nature, 581, 262. https://doi.org/10.1038/d41586-020-01474-7
  • Andres, F., Schwill, M., Boersma, Y. L., & Plückthun, A. (2020). High-Throughput Generation of Bispecific Binding Proteins by Sortase A-Mediated Coupling for Direct Functional Screening in Cell Culture Molecular Cancer Therapeutics, 19, 1080–1088. https://doi.org/10.1158/1535-7163.MCT-19-0633
  • Petrenčáková, M., Filandr, F., Hovan, A., Yassaghi, G., Man, P., Kožár, T., Schwer, M.-S., Jancura, D., Plückthun, A., Novák, P., Miškovský, P., Bánó, G., & Sedlák, E. (2020). Photoinduced damage of AsLOV2 domain is accompanied by increased singlet oxygen production due to flavin dissociation Scientific Reports, 10, 4119. https://doi.org/10.1038/s41598-020-60861-2
  • Ernst, P., Zosel, F., Reichen, C., Nettels, D., Schuler, B., & Plückthun, A. (2020). Structure-Guided Design of a Peptide Lock for Modular Peptide Binders ACS Chemical Biology, 15, 457–468. https://doi.org/10.1021/acschembio.9b00928
  • Mittl, P. R., Ernst, P., & Plückthun, A. (2020). Chaperone-assisted structure elucidation with DARPins Current Opinion in Structural Biology, 60, 93–100. https://doi.org/10.1016/j.sbi.2019.12.009
  • Voskuil, J. L. A., Bandrowski, A., Begley, C. G., Bradbury, A. R. M., Chalmers, A. D., Gomes, A. V., Hardcastle, T., Lund-Johansen, F., Plückthun, A., Roncador, G., Solache, A., Taussig, M. J., Trimmer, J. S., Williams, C., & Goodman, S. L. (2020). The Antibody Society’s antibody validation webinar series. MAbs, 12, e1794421. https://doi.org/10.1080/19420862.2020.1794421

• 2019

  • Balakrishnan, A., Rajan, A., Salter, A. I., Kosasih, P. L., Wu, Q., Voutsinas, J., Jensen, M. C., Plückthun, A., & Riddell, S. R. (2019). Multispecific Targeting with Synthetic Ankyrin Repeat Motif Chimeric Antigen Receptors Clinical Cancer Research, 25, 7506–7516. https://doi.org/10.1158/1078-0432.CCR-19-1479
  • Chernyavska, M., Schmid, M., Freitag, P. C., Palacio-Castañeda, V., Piruska, A., Huck, W. T. S., Plückthun, A., & Verdurmen, W. P. R. (2019). Unravelling receptor and RGD motif dependence of retargeted adenoviral vectors using advanced tumor model systems Scientific Reports, 9, 18568. https://doi.org/10.1038/s41598-019-54939-9
  • Ehrenmann, J., Schöppe, J., Klenk, C., & Plückthun, A. (2019). New views into class B GPCRs from the crystal structure of PTH1R FEBS Journal, 286, 4852–4860. https://doi.org/10.1111/febs.15115
  • Ernst, P., Honegger, A., van der Valk, F., Ewald, C., Mittl, P. R. E., & Plückthun, A. (2019). Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts Scientific Reports, 9, 16162. https://doi.org/10.1038/s41598-019-52121-9
  • Dunne, M., Rupf, B., Tala, M., Qabrati, X., Ernst, P., Shen, Y., Sumrall, E., Heeb, L., Plückthun, A., Loessner, M. J., & Kilcher, S. (2019). Reprogramming Bacteriophage Host Range through Structure-Guided Design of Chimeric Receptor Binding Proteins Cell Reports, 29, 1336-1350.e4. https://doi.org/10.1016/j.celrep.2019.09.062
  • Ernst, P., Plückthun, A., & Mittl, P. R. E. (2019). Structural analysis of biological targets by host:guest crystal lattice engineering Scientific Reports, 9, 15199. https://doi.org/10.1038/s41598-019-51017-y
  • Renko, M., Fiedler, M., Rutherford, T. J., Schaefer, J. V., Plückthun, A., & Bienz, M. (2019). Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome Proceedings of the National Academy of Sciences of the United States of America, 116, 20977–20983. https://doi.org/10.1073/pnas.1912705116
  • Brandl, F., Merten, H., Zimmermann, M., Béhé, M., Zangemeister-Wittke, U., & Plückthun, A. (2019). Influence of size and charge of unstructured polypeptides on pharmacokinetics and biodistribution of targeted fusion proteins Journal of Controlled Release, 307, 379–392. https://doi.org/10.1016/j.jconrel.2019.06.030
  • Lorenzer, C., Streußnig, S., Tot, E., Winkler, A.-M., Merten, H., Brandl, F., Sayers, E. J., Watson, P., Jones, A. T., Zangemeister-Wittke, U., Plückthun, A., & Winkler, J. (2019). Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing European Journal of Pharmaceutics and Biopharmaceutics, 141, 37–50. https://doi.org/10.1016/j.ejpb.2019.05.015
  • Radom, F., Paci, E., & Plückthun, A. (2019). Computational Modeling of Designed Ankyrin Repeat Protein Complexes with Their Targets Journal of Molecular Biology, 431, 2852–2868. https://doi.org/10.1016/j.jmb.2019.05.005
  • Stüber, J. C., Kast, F., & Plückthun, A. (2019). High-Throughput Quantification of Surface Protein Internalization and Degradation ACS Chemical Biology, 14, 1154–1163. https://doi.org/10.1021/acschembio.9b00016
  • Campanacci, V., Urvoas, A., Cantos-Fernandes, S., Aumont-Nicaise, M., Arteni, A.-A., Velours, C., Valerio-Lepiniec, M., Dreier, B., Plückthun, A., Pilon, A., Poüs, C., Minard, P., & Gigant, B. (2019). Insight into microtubule nucleation from tubulin-capping proteins Proceedings of the National Academy of Sciences of the United States of America, 116, 9859–9864. https://doi.org/10.1073/pnas.1813559116
  • Andres, F., Iamele, L., Meyer, T., Stüber, J. C., Kast, F., Gherardi, E., Niemann, H. H., & Plückthun, A. (2019). Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking Journal of Molecular Biology, 431, 2020–2039. https://doi.org/10.1016/j.jmb.2019.03.024
  • Meksiriporn, B., Ludwicki, M. B., Stephens, E. A., Jiang, A., Lee, H.-C., Waraho-Zhmayev, D., Kummer, L., Brandl, F., Plückthun, A., & DeLisa, M. P. (2019). A survival selection strategy for engineering synthetic binding proteins that specifically recognize post-translationally phosphorylated proteins Nature Communications, 10, 1830. https://doi.org/10.1038/s41467-019-09854-y

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