Publications of the Plückthun Group

ZORA Publication List

Publications

• 2016

  • Batyuk, A., Wu, Y., Honegger, A., Heberling, M. M., & Plückthun, A. (2016). DARPin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography Journal of Molecular Biology, 428, 1574–1588. https://doi.org/10.1016/j.jmb.2016.03.002
  • Schütz, M., Batyuk, A., Klenk, C., Kummer, L., de Picciotto, S., Gülbakan, B., Wu, Y., Newby, G. A., Zosel, F., Schöppe, J., Sedlák, E., Mittl, P. R. E., Zenobi, R., Wittrup, K. D., & Plückthun, A. (2016). Generation of Fluorogen-Activating Designed Ankyrin Repeat Proteins (FADAs) as Versatile Sensor Tools Journal of Molecular Biology, 428, 1272–1289. https://doi.org/10.1016/j.jmb.2016.01.017
  • Hansen, S., Tremmel, D., Madhurantakam, C., Reichen, C., Mittl, P. R. E., & Plückthun, A. (2016). Structure and Energetic Contributions of a Designed Modular Peptide-Binding Protein with Picomolar Affinity Journal of the American Chemical Society, 138, 3526–3532. https://doi.org/10.1021/jacs.6b00099
  • Jones, T. D., Carter, P. J., Plückthun, A., & et al. (2016). The INNs and outs of antibody nonproprietary names MAbs, 8, 1–9. https://doi.org/10.1080/19420862.2015.1114320
  • Klenk, C., Ehrenmann, J., Schütz, M., & Plückthun, A. (2016). A generic selection system for improved expression and thermostability of G protein-coupled receptors by directed evolution Scientific Reports, 6, 21294. https://doi.org/10.1038/srep21294
  • Reichen, C., Madhurantakam, C., Hansen, S., Grütter, M. G., Plückthun, A., & Mittl, P. R. E. (2016). Structures of designed armadillo-repeat proteins show propagation of inter-repeat interface effects Acta Crystallographica. Section D: Structural Biology, 72, 168–175. https://doi.org/10.1107/S2059798315023116
  • Ahmad, S., Pecqueur, L., Dreier, B., Hamdane, D., Aumont-Nicaise, M., Plückthun, A., Knossow, M., & Gigant, B. (2016). Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin Scientific Reports, 6, 28922. https://doi.org/10.1038/srep28922
  • Schütz, M., Schöppe, J., Sedlák, E., Hillenbrand, M., Nagy-Davidescu, G., Ehrenmann, J., Klenk, C., Egloff, P., Kummer, L., & Plückthun, A. (2016). Directed evolution of G protein-coupled receptors in yeast for higher functional production in eukaryotic expression hosts Scientific Reports, 6, 21508. https://doi.org/10.1038/srep21508
  • Tamaskovic, R., Schwill, M., Nagy-Davidescu, G., Jost, C., Schaefer, D. C., Verdurmen, W. P. R., Schaefer, J. V., Honegger, A., & Plückthun, A. (2016). Intermolecular biparatopic trapping of ErbB2 prevents compensatory activation of PI3K/AKT via RAS-p110 crosstalk Nature Communications, 7, 11672. https://doi.org/10.1038/ncomms11672
  • Reichen, C., Hansen, S., Forzani, C., Honegger, A., Fleishman, S. J., Zhou, T., Parmeggiani, F., Ernst, P., Madhurantakam, C., Ewald, C., Mittl, P. R. E., Zerbe, O., Baker, D., Caflisch, A., & Plückthun, A. (2016). Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition Journal of Molecular Biology, 428, 4467–4489. https://doi.org/10.1016/j.jmb.2016.09.012
  • Hanauer, J. R., Gottschlich, L., Riehl, D., Rusch, T., Koch, V., Friedrich, K., Hutzler, S., Prüfer, S., Friedel, T., Hanschmann, K.-M., Münch, R. C., Jost, C., Plückthun, A., Cichutek, K., Buchholz, C. J., & Mühlebach, M. D. (2016). Enhanced lysis by bispecific oncolytic measles viruses simultaneously using HER2/neu or EpCAM as target receptors Molecular Therapy : Oncolytics, 3, 16003. https://doi.org/10.1038/mto.2016.3

• 2015

  • Merten, H., Brandl, F., Plückthun, A., & Zangemeister-Wittke, U. (2015). Antibody-drug conjugates for tumor targeting-novel conjugation chemistries and the promise of non-igg binding proteins Bioconjugate Chemistry, 26, 2176–2185. https://doi.org/10.1021/acs.bioconjchem.5b00260
  • Bradbury, A. R. M., & Plückthun, A. (2015). Getting to reproducible antibodies: the rationale for sequenced recombinant characterized reagents Protein Engineering, Design & Selection, 28, 303–305. https://doi.org/10.1093/protein/gzv051
  • Fleishman, S. J., & Plückthun, A. (2015). Editorial overview: Protein design and evolution-new protein architectures, evolutionary fine-tuning and analysis Current Opinion in Structural Biology, 33, v–vi. https://doi.org/10.1016/j.sbi.2015.08.002
  • König, I., Zarrine-Afsar, A., Aznauryan, M., Soranno, A., Wunderlich, B., Dingfelder, F., Stüber, J. C., Plückthun, A., Nettels, D., & Schuler, B. (2015). Single-molecule spectroscopy of protein conformational dynamics in live eukaryotic cells Nature Methods, 12, 773–779. https://doi.org/10.1038/nmeth.3475
  • Sedlák, E., Schaefer, J. V., Marek, J., Gimeson, P., & Plückthun, A. (2015). Advanced analyses of kinetic stabilities of iggs modified by mutations and glycosylation Protein Science, 24, 1100–1113. https://doi.org/10.1002/pro.2691
  • Ewald, C., Christen, M. T., Watson, R. P., Mihajlovic, M., Zhou, T., Honegger, A., Plückthun, A., Caflisch, A., & Zerbe, O. (2015). A combined NMR and computational approach to investigate peptide binding to a designed armadillo repeat protein Journal of Molecular Biology, 427, 1916–1933. https://doi.org/10.1016/j.jmb.2015.02.022
  • Bradbury, A. M., & Plückthun, A. (2015). Antibodies: validate recombinants once Nature, 520, 295. https://doi.org/10.1038/520295b
  • Egloff, P., Deluigi, M., Heine, P., Balada, S., & Plückthun, A. (2015). A cleavable ligand column for the rapid isolation of large quantities of homogeneous and functional neurotensin receptor 1 variants from E. coli Protein Expression and Purification, 108, 106–114. https://doi.org/10.1016/j.pep.2014.10.006
  • Friedel, T., Hanisch, L. J., Muth, A., Honegger, A., Abken, H., Plückthun, A., Buchholz, C. J., & Schneider, I. C. (2015). Receptor-targeted lentiviral vectors are exceptionally sensitive toward the biophysical properties of the displayed single-chain Fv Protein Engineering, Design & Selection, 28, 93–106. https://doi.org/10.1093/protein/gzv005

Pagination