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Department of Biochemistry

Publications 2024

by date of publication in PubMed, most recent at the top:

2024

Saha, A., Ahsan, M., Arantes, PR., Schmitz, M., Chanez, C., Jinek, M. & Palermo, G. An alpha-helical lid guides the target DNA toward catalysis in CRISPR-Cas12a. Nat Commun 15, 1473 (2024). PMID: 38368461.

Grabenhorst, L., Sturzenegger, F., Hasler, M., Schuler, B. & Tinnefeld, P. Single-Molecule FRET at 10 MHz Count Rates. J Am Chem Soc 146, 3539-3544 (2024). PMID: 38266173.

Tinzl, M., Diedrich, JV., Mittl, PRE., Clémancey, M., Reiher, M., Proppe, J., Latour, JM. & Hilvert, D. Myoglobin-Catalyzed Azide Reduction Proceeds via an Anionic Metal Amide Intermediate. J Am Chem Soc 146, 1957-1966 (2024). PMID: 38264790.

Abdul-Ridha, A., de Zhang, LA., Betrie, AH., Deluigi, M., Vaid, TM., Whitehead, A., Zhang, Y., Davis, B., Harris, R., Simmonite, H., Hubbard, RE., Gooley, PR., Plückthun, A., Bathgate, RAD., Chalmers, DK. & Scott, DJ. Identification of a Novel Subtype-Selective α1B  Adrenoceptor Antagonist. ACS Chem Neurosci  15, 671-684 (2024). PMID: 38238043.

Finocchio, G., Koopal, B., Potocnik, A., Heijstek, C., Westphal, AH., Jinek, M. & Swarts, DC. Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA. Nucleic Acids Res [Epub ahead of print] (2024). PMID: 38224450.

Jungfer, K., Sigg, A. & Jinek, M. Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2. Nucleic Acids Res 52, 462-473 (2024). PMID: 38033326.