Publications 2024

by date of publication in PubMed, most recent at the top:

2024

Ivanova, JR., Benk, AS., Schaefer, JV., Dreier, B., Hermann, LO., Plückthun, A., Missirlis, D. & Spatz, JP. Designed Ankyrin Repeat Proteins as Actin Labels of Distinct Cytoskeletal Structures in Living Cells. ACS Nano 18, 8919-8933 (2024). PMID: 38489155.

Corbeski, I., Vargas-Rosales, PA., Bedi, RK., Deng, J., Coelho, D., Braud, E., Iannazzo, L., Li, Y., Huang, D., Ethève-Quelquejeu, M., Cui, Q. & Caflisch, A. The catalytic mechanism of the RNA methyltransferase METTL3. Elife 12, (2024). PMID: 38470714.

Weber, Y., Böck, D., Ivașcu, A., Mathis, N., Rothgangl, T., Ioannidi, EI., Blaudt, AC., Tidecks, L., Vadovics, M., Muramatsu, H., Reichmuth, A., Marquart, KF., Kissling, L., Pardi, N., Jinek, M. & Schwank, G. Enhancing prime editor activity by directed protein evolution in yeast. Nat Commun 15, 2092 (2024). PMID: 38453904.

Pacesa, M., Pelea, O. & Jinek, M. Past, present, and future of CRISPR genome editing technologies. Cell 187, 1076-1100 (2024). PMID: 38428389.

Errani, F., Invernizzi, A., Herok, M., Bochenkova, E., Stamm, F., Corbeski, I., Romanucci, V., Di Fabio, G., Zálešák, F. & Caflisch, A. Proteolysis Targeting Chimera Degraders of the METTL3-14 m6A-RNA Methyltransferase. JACS Au 4, 713-729 (2024). PMID: 38425900.

Thalmann, L., Martin-Gonzalez, N., Brücher, D., Plückthun, A., de Pablo, PJ., Suomalainen, M. & Greber, UF. Gutless Helper-Dependent and First-Generation HAdV5 Vectors Have Similar Mechanical Properties and Common Transduction Mechanisms. Hum Gene Ther 35, 163-176 (2024). PMID: 38386500.

Saha, A., Ahsan, M., Arantes, PR., Schmitz, M., Chanez, C., Jinek, M. & Palermo, G. An alpha-helical lid guides the target DNA toward catalysis in CRISPR-Cas12a. Nat Commun 15, 1473 (2024). PMID: 38368461.

Grabenhorst, L., Sturzenegger, F., Hasler, M., Schuler, B. & Tinnefeld, P. Single-Molecule FRET at 10 MHz Count Rates. J Am Chem Soc 146, 3539-3544 (2024). PMID: 38266173.

Tinzl, M., Diedrich, JV., Mittl, PRE., Clémancey, M., Reiher, M., Proppe, J., Latour, JM. & Hilvert, D. Myoglobin-Catalyzed Azide Reduction Proceeds via an Anionic Metal Amide Intermediate. J Am Chem Soc 146, 1957-1966 (2024). PMID: 38264790.

Abdul-Ridha, A., de Zhang, LA., Betrie, AH., Deluigi, M., Vaid, TM., Whitehead, A., Zhang, Y., Davis, B., Harris, R., Simmonite, H., Hubbard, RE., Gooley, PR., Plückthun, A., Bathgate, RAD., Chalmers, DK. & Scott, DJ. Identification of a Novel Subtype-Selective α1B  Adrenoceptor Antagonist. ACS Chem Neurosci  15, 671-684 (2024). PMID: 38238043.

Finocchio, G., Koopal, B., Potocnik, A., Heijstek, C., Westphal, AH., Jinek, M. & Swarts, DC. Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA. Nucleic Acids Res [Epub ahead of print] (2024). PMID: 38224450.

Jungfer, K., Sigg, A. & Jinek, M. Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2. Nucleic Acids Res 52, 462-473 (2024). PMID: 38033326.